Evidence-based PEM
The febrile infant
Occult Bacteremia
Safety, Immunogeniticy, and induction of immunologic memory by a serogroup C Meningococcal conjugate vaccine in infants. (JAMA 2000. Abstract).
Predictors of Occult Pneumococcal Bacteremia in Young Febrile Children
(Ann Emerg Med, 1998, abstract)
Safety and immunogenicity of heptavalent pneumococcal vaccine conjugated to CRM197 in US infants. (Pediatrics 1998.Abstact).
Intramuscular versus oral antibiotic therapy for the prevention of meningitis and other bacterial sequelae in young, febrile children at risk for occult bacteremia (J Ped, 1994, abstract)
Antibiotic administration to treat possible occult bacteremia in febrile children
(NEJM 1987, abstract)
Fever in the young infant
Febrile infants at low risk for serious bacterial infection--an appraisal of the Rochester criteria and implications for management. Febrile Infant Collaborative Study Group.
(Pediatrics, 1994, abstract) - ["the Rochester Criteria"]
Outpatient Management without Antibiotics of Fever in Selected Infants
(NEJM,1993, abstract) - ["the Philadelphia Criteria"]
Outpatient treatment of febrile infants 28 to 89 days of age with intramuscular administration of ceftriaxone (J ped,1992, abstract) - ["the Boston Criteria"
]
Does acetaminophen treat fever in children? (Ann Emerg Med, 2003, abstract)
Spesis
Corticosteroids for severe sepsis and septic shock: a systematic review and meta-analysis
(BMJ, 2004, full article)
